Sodium Tetradecyl Sulfate ( Tetradecyl sodiuM sulfate )

产品货号. M28806 CAS No. 1191-50-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Sodium Tetradecyl Sulfate
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Sodium Tetradecyl Sulfate is a detergent sclerosant with antithrombotic effects and commonly used for the treatment of varicose veins.
产品描述

Sodium Tetradecyl Sulfate is a detergent sclerosant with antithrombotic effects and commonly used for the treatment of varicose veins.(In Vitro):Proteins C, S and antithrombin (AT) were assayed in normal plasma treated with increasing concentrations of Sodium Tetradecyl Sulfate. High concentration (>0.6%) Sodium Tetradecyl Sulfate significantly destroyed proteins C, S and AT. Sodium Tetradecyl Sulfate potentiated the anticoagulant effect of APC. Sodium Tetradecyl Sulfate mimicked AT and demonstrated significant anti-Xa and anti-IIa activity. STS demonstrated a weak anticoagulant profile to heparin. It also significantly potentiated the anticoagulant effect of heparin.(In Vivo):i.v. + p.v. injection of Sodium Tetradecyl Sulfate and hydroxy polyethoxy dodecan provided a high degree of efficacy as regards vein occlusion. On the other hand, i.v. + p.v. injection induced a severe inflammation and necrosis of the tissues surrounding the sclerosed vein.
同义词

Tetradecyl sodiuM sulfate
通路

Others
靶点

Other Targets
受体

NMDA
研究领域

——
适应症

——

1.Walters MR, et al. Early clinical experience with the novel NMDA receptor antagonist CNS 516Br J Clin Pharmacol. 2002 Mar;53(3):305-11.

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